European Journal of Human Genetics (2007)
15, 288–293. doi:10.1038/sj.ejhg.5201771;
published online 24 January 2007
Africans in Yorkshire? The deepest-rooting clade of the Y phylogeny within an English genealogy :shock: (Is this you Mgt23... ;) )
Turi E King1, Emma J Parkin1, Geoff Swinfield2, Fulvio Cruciani3, Rosaria Scozzari3, Alexandra Rosa4, Si-Keun Lim5, Yali Xue5, Chris Tyler-Smith5 and Mark A Jobling1
1Department of Genetics, University of Leicester, Leicester, UK
2GSGS, 14 Beaconsfield Road, Mottingham, London, UK
3Department of Genetics and Molecular Biology, Università degli Studi di Roma 'La Sapienza', Rome, Italy
4Human Genetics Laboratory, University of Madeira, Funchal, Portugal
5Wellcome Trust Sanger Institute, Hinxton, UK
Correspondence: Professor MA Jobling, Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK. Tel: +44 116 252 3427; Fax: +44 116 252 3378; E-mail: http://www.fluxus-engineering.com/sharenet.htm (http://www.fluxus-engineering.com/sharenet.htm)) using variance-based weighting as described.20 Weighting for hgA1 was based on variance in all hgA1 chromosomes, whereas weighting for the R surname network was based on variance observed in 291 British hgR1b chromosomes.
Time-to-most-recent-common-ancestor (TMRCA) was estimated within Network from the rho-statistic, using a 35-year generation time,15 and a mean per-locus, per-generation mutation rate of 2 times 10-3.21, 22, 23
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Results
As part of a survey of British Y-chromosome diversity, we recruited a set of 421 males, who described themselves as British, and whose paternal grandfathers were born in Britain. The Y chromosomes of these males were typed using a set of 11 binary markers,15 including M145 (defining superhaplogroup DE) and M89 (defining superhaplogroup F). All chromosomes carried the derived allele at one or other of these two markers, with a single exception, in male GB1757, which could in principle belong to hgA, B or C (see phylogeny in Figure 1). Further testing, including the markers M91 and M31, gave the surprising result that it belonged to hgA, within the sublineage A1.
Figure 1.
Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact http://www.yhrd.org (http://www.yhrd.org)) finds no matches among 15 815 chromosomes worldwide, emphasizing its rarity. Also, when the haplotypes of the other hgA1 chromosomes are used in similar searches, they find only self-matches in the populations from which they derive, underlining the scarcity and African-specificity of hgA1.
http://www.nature.com/ejhg/journal/v15/ ... 1771a.html (http://www.nature.com/ejhg/journal/v15/n3/full/5201771a.html)
i'm black now. Harsh CSR harsh.......
Quote from: "mgt23"i'm black now. Harsh CSR harsh.......
I'd prefer part "Afro"... She's got to have it you know... you should get "tested" just for peace of mind... :)