Vitamin B-17 and Apricots

[Rockclimber]

Piggbacking of of this:  http://www.thecrowhouse.com/cncr.html

I found this:  http://www.apricotpower.com/retailers.asp

For the record: I don't have cancer but I have read that B-17 allegedly can cure it. Literal food for thought. Just another proactive measure.

[bigwaga]

www.cancure.com
www.worldwithoutcancer.co.uk

I was very impressed mr Griffens, world without cancer doc,i know it was stolen form eustice, but it still great. l also listened to dr lorraine day. everything i have seen since then allways points to a nutritional cure for the big C. I no longer fear the big C cos i have at least 6 apricot kernals a day.

nd don't fall for the crap that you will be poisned if you eat too many of them, I've downed 30 at once and been fine.

if you want any info email me at mailto:johngcrockett@live.com">johngcrockett@live.com

"read the protocalls,there you will learn it all.

John

[bigwaga]

sorry allways getting my com and orgs confused
 www.cancure.org

john

[Helphand]

Interesting stuff, aka laetrile, also McHarrison (sp?) the English-Army-In-India doctor/MD who in the 1930s(?) observed the Hunzas in northern India and noted their long life span and freedom from cancer and other "Western" diseases which he attributed to "the soil of disordered living"; he noted also the Hunzas' veg. diet rich in ... apricots, of which they ate the pits/kernels.  Similar effect with apple core pips.

Reservation: go to youtube and look up cancer cures and so on and you get lots more... like, bicarbonate of soda being pulsed into rectum for cancer blockage and also into lungs for growths; dilute hydrogen peroxide drinking; 'atomised' silver (can't recall proper term off the cuff) for anti-bacterial effect (long established in burns treatment of course) and more...

[CrackSmokeRepublican]

Most alternative Cures for Cancer (that is non-radiation) generally fall into two categories:

1. Yeast-alkaline based substances cause - White Cancer

2. Genetic component related to ATP-Krebs Cycle-refined Sugar which are shut off by constrictive agents that prevents nutrients supplying cancerous tissues.

3. Shutting down lactate usage

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#22)
Re: Cannabis Cures Cancer - Testimony

Postby CrackSmokeRepublican » Sat Jan 23, 2010 3:28 pm
Okay... here's my list. I'm not an expert on this and this is just my opinion. Cancers feed on ATP and Sugar imbalances. Starve Cancers by removing Sugars (Glucose). Weed is very good for people in Pain... IMHO. :

1. Methylgloxal - MANUKA HONEY one of a few natural substances containing this - Retine is the substance the body uses -- (Starves Cancerous Cells)
2. HHEA (Hydroxy-ethyl-adenosine-analogs) found in Chinese Cordyceps and other Japanese Shrooms -- (ATP)
3. Elimination of all refined sugars from diet -- (Starves Cancerous Cells)
4. Hemp Oil - yes. The release of Leptin and other Hormones in the body -- (ATP)
5. Baking Soda and the PH balance is definitely important -- (ATP and reduction of Fungal properties)
6. Creatine and IGF-1 (Creatine and a minimal amount of IGF-1 to assist in ATP generation)
7. Exercise with Strength Training to allow muscles to increase ATP.
8. Trace Minerals (zinc, Chromium, Selenium, B-Vitamins, Vitamin E, Vitamin D, etc.) - the body cannot utilize sugars for ATP without oxidation unless the Vitamins and Minerals used by the body for sugar metabolizim are present.
9. Reduction of Oxidative Stress and Cortisol (Alpha-Lipoic-Acid, L-Carnosine-Acetyl-L-Carnitine, Cinnamon tea, Folic Acid, Vitamin C, Conjugated Linoleic Acid ). Also reduction of excessive Homocysteine and Cortisol.
10. Cancer cells hijack the blood flows in order to grow. It will only "grow" when proper ATP-Sugar metabolism-PH balance and Methylation are not present. There is a link with this :

    ACTH (adrenocorticotropin), which is secreted in excess by tumors of the pituitary gland, situated at the base of the brain and, which controls growth, metabolism and reproduction

- stimulates Cortisol production. ( Which THC may suppress?)

11. Sam-E supplementation:

    DNA METHYLATION. There is nothing more fundamental to human life than DNA. It's the genetic "software" which runs the cells and contains the genetic code for every living thing. When SAM-e reacts with DNA by donating a methyl group, it allows our genes to spring into action. It's like hitting the "on" switch on a computer; DNA methylation is the operating system of the body, helping it to regulate important processes such as cellular growth and repair, production of immune cells to fight disease, wound healing, and reproduction. The undermethylation of DNA is believed to be a causal factor in cancer, because it could hamper the body's ability to repair damaged cells before they turn cancerous.



12. Restore proper levels of Lactic Acid

In sum, we are looking at an approach here that will "starve" the Cancer Cells via Methlygloxal while supplying cells with ATP for proper generation and Mitochondrial activity. Cancer is both a hijacking of the energy generation properties of cells along with an attack on the immune system (NK, T-Cells,Cytokines). Much of Cancer's action along with Fungi's action involves proper Methylation. Certain Cancerous conditions in different parts of the body can have imbalances due to infections, over expressions of certain hormones, inadequate supplies of ATP, Oxidation from either internal factors or outside agents (radiation). Lack of Vitamin D can lead to cancer as well as an extreme lack of Folates.


"Mitochondrial dysfunction is a common phenotype in aging and cancer. "


    Cancer and ketones
    Dr Fine is looking at metabolic management of cancers. Cancers express uncoupling protein 2 (UCP2). UCP2 plugs in to the mitochondrial inner membrane, allows protons through, lowers the voltage across the membrane and so reduces both ATP and free radical production by the mitochondria. It might not be as physiological as UCP3, more of a survival tactic in hyper energetic states. UCP2 is not commonly present in normal tissues.

    Lack of respiration drives the use of glucose-lactate fermentation, adapted to the the hypoxic environment which is a common location of cancer cells.
    http://high-fat-nutrition.blogspot.com/ ... tones.html






    Dysfunctional mitochondria, not oxygen insufficiency, cause cancer cells to produce inordinate amounts of lactic acid. The impact of this on the treatment of cancer.

    It has been known for decades that cancer cells produce excessive amounts of lactic acid. The fact that most cancers have poor vascular systems has led cancer scientists to assume that such cells are deprived of a normal supply of oxygen. Researchers believe that without sufficient oxygen, cancer cells must revert to fermentation for their energy supply and this is what causes them to produce excessive lactic acid. I challenge this traditional assumption and suggest instead that cancer cells have dysfunctional mitochondria, which prevent their use of the citric acid cycle. Consequently, pyruvic acid, the normal end product of glycolysis, which normally would enter the mitochondria for its total combustion into energy, is instead converted to lactic acid. Evidence exists to support this hypothesis which, when acknowledged, could dynamically impact both cancer research and the treatment of all forms of cancer.



Some better links on recent Cancer research:
http://curezone.com/forums/am.asp?i=1185987
http://www.cancerfightingstrategies.com ... yoxal.html -- the cells can use Methylgyoxal instead of Glucose.
http://www.annalsnyas.org/cgi/content/a ... 1012/1/153
http://www.taxtyranny.ca/images/HTML/Aids/Aids112.html
http://high-fat-nutrition.blogspot.com/ ... tones.html
http://cancerci.com/content/9/1/14
http://www.newtreatments.org/Cancer%20Treatment/ga/366
http://www.sciencedaily.com/releases/20 ... 171325.htm

--The CSR

    Many tumors have cells that burn fuel for activities in different ways. Tumor cells near blood vessels have adequate oxygen sources and can either burn glucose like normal cells, or lactic acid (lactate). Tumor cells further from vessels are hypoxic and inefficiently burn a lot of glucose to keep going. In turn, they produce lactate as a waste product.

    Tumor cells with good oxygen supply actually prefer to burn lactate, which frees up glucose to be used by the less-oxygenated cells. But when the researchers cut off the cells' ability to use lactate, the hypoxic cells didn't get as much glucose.

    For the dangerous hypoxic cells, "it is glucose or death," said Pierre Sonveaux, professor in the UCL Unit of Pharmacology & Therapeutics and lead author of the study, published in the Nov. 20 online edition of the Journal of Clinical Investigation. He formerly worked with Dr. Dewhirst at Duke.

    The next challenge was to discover how lactate moved into tumor cells. Because lactate recycling exists in exercising muscle to prevent cramps, the researchers imagined that the same molecular machinery could be used by tumor cells.

    "We discovered that a transporter protein of muscle origin, MCT1, was also present in respiring tumor cells," said Dewhirst. The team used chemical inhibitors of MCT1 and cell models in which MCT1 had been deleted to learn its role in delivering lactate.
    http://www.sciencedaily.com/releases/20 ... 171325.htm



Finally, Fungi tend to produce Lactic Acid which is an "Additive" in many foods -- it think this might be a key between Fungi-Cancer-Glucose Metabolism and Lactic Acid:

    Lactic acid is used extensively by the food industry as a flavour agent, preservative, and acidity adjuster in foods. A review published in 1995 (FEMS Microbiol. Rev. Vol. 16, pp. 221-231) stated that 85 per cent of lactic acid was used in food and food-related applications in the USA.

    The review is a timely reminder of the potential of the fungi to produce lactic acid more cost-effectively than other sources, notably bacteria. Prices for lactic acid have been rising in recent years with producers like Purac and Galactic announcing hikes.

    Energy costs for example have doubled in the last 12 to 24 month and the costs for carbohydrates have gone up by 40 to 60 per cent.

    The surging cost for carbohydrates is explained by the restructuring of the sugar regime in the European Union and the strongly increasing demand for carbohydrates to produce bio-ethanol.

    An advantage offered over other methods of lactic acid production, suggest the authors, is that other, less expensive carbohydrate sources, including refined sugars, molasses, raw starch materials and even lignocellulose using fungal strains of Rhizopus genus.

    The review, published in the Biochemical Engineering Journal, also points out that the Rhizopus strains only generate the l-lactic acid isomer, which is the preferred form for the food industry since elevated levels of the d-isomer form are reported to be harmful to humans.



http://www.foodnavigator-usa.com/Produc ... cid-source

viewtopic.php?f=18&t=9170&hilit=Cancer&start=15#p35621

[CrackSmokeRepublican]

Also of interest -- keep in mind that Cordyceps delivers enhanced levels of Oxygen throughout the body.
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viewtopic.php?f=18&t=10944&p=41231

Recent Scottish Cancer Discoveries
     29 December 2009

    Scientists discover how wild mushroom cancer drug works

    Cordyceps militaris growing on a moth pupa

    The drug was first isolated from a parasitic mushroom

    Scientists have discovered how a promising cancer drug, first discovered in a wild mushroom, works.

    The University of Nottingham team believe their work could help make the drug more effective, and useful for treating a wider range of cancers.

    Cordycepin, commonly used in Chinese medicine, was originally extracted from a rare kind of parasitic mushroom that grows on caterpillars.

    The study will appear in the Journal of Biological Chemistry.

    The cordyceps mushroom has been studied by medical researchers for some time - the first scientific publication on cordycepin was in 1950.

    However, although the drug showed great promise, it was quickly degraded in the body.

    It can be given with another drug to combat this - but the second drug can produce side effects that limit its potential use.

    As a result, researchers turned their interest to other potential candidate drugs, and exactly how cordycepin worked on the body's cells remained unclear.

    It could lay the groundwork for the design of new cancer drugs that work on the same principle.

    Researcher Dr Cornelia de Moor said: "Our discovery will open up the possibility of investigating the range of different cancers that could be treated with cordycepin.

    "It will be possible to predict what types of cancers might be sensitive and what other cancer drugs it may effectively combine with.

    "It could also lay the groundwork for the design of new cancer drugs that work on the same principle."

    The researchers have also developed a method to test how effective the drug is in new preparations, and combinations with other drugs, which might solve the problem of degradation more satisfactorily.

    Dr De Moor said: "This is a great advantage as it will allow us to rule out any non-runners before anyone considers testing them in animals."

    The Nottingham team observed two effects on the cells - at a low dose cordycepin inhibits the uncontrolled growth and division of the cells, and at high doses it stops cells from sticking together, which also inhibits growth.

    The knowledge generated by this research demonstrates the mechanisms of drug action and could have an impact on one of the most important challenges to health


    Both of these effects probably have the same underlying mechanism - that cordycepin interferes with how cells make proteins.

    At low doses cordycepin interferes with the production of mRNA, the molecule that gives instructions on how to assemble a protein.

    And at higher doses it has a direct impact on the making of proteins.

    Professor Janet Allen is director of research at the Biotechnology and Biological Sciences Research Council, which funded the study.

    She said: "This project shows that we can always return to asking questions about the fundamental biology of something in order to refine the solution or resolve unanswered questions.

    "The knowledge generated by this research demonstrates the mechanisms of drug action and could have an impact on one of the most important challenges to health."



http://news.bbc.co.uk/2/hi/health/8428340.stm

----------------



    Scientists make cancer cells vanish

    * Cancer Research UK said results were encouraging

    EXCLUSIVE: Helen Puttick, Health Correspondent


    21 Apr 2010

    Scottish scientists have made cancer tumours vanish within 10 days by sending DNA to seek and destroy the cells.

    The system, developed at Strathclyde and Glasgow universities, is being hailed as a breakthrough because it appears to eradicate tumours without causing harmful side-effects. A leading medical journal has described the results so far as remarkable, while Cancer Research UK said they were encouraging.

    Dr Christine Dufes, a lecturer at the Strathclyde Institute of Pharmacy and Biomedical Sciences and leader of the research, said: "The tumours were completely gone within 10 days. It is fantastic. When you talk about 10 days that is the time frame for curing a cold. Imagine if within 10 days you could completely make a tumour disappear."

    Researchers around the world are trying to find ways to use genes as a cancer treatment, but one problem is ensuring they attack the tumour without destroying healthy tissue.

    In laboratory experiments the Strathclyde research team used a plasma protein called transferrin, which carries iron through the blood, to deliver the therapeutic DNA to the right spot. Once in situ the DNA produced a protein that attacked the tumour cells.

    The findings have been published in the Journal of Controlled Release, with an accompanying comment from editor Professor Kinam Park, of Purdue University, Indiana, saying other attempts to target genes at cancer cells have "seldom shown complete disappearance of tumours".

    The research was initially supported with a grant from charity Tenovus Scotland, which supports the work of young scientists to help their ideas get off the ground.



http://www.heraldscotland.com/news/heal ... -1.1022114

[bigwaga]

I've just read "Aids, Opium, diamond and Empire" by Nancy Turner Banks MD. There is a section in that book that points to Otto Warburg for discovering that cancer is caused by the energy system within the cells being disrupted. The mitochondria not being able to produce the energy that the cell needs and that when this happens the cell had a few choices, it can either Die, degenerate (i'e disease) or revert to a pre embryonic state where it is trying to survive independently from the cells around it (i.e. it has no communication with the other cells) therefore it will replicate without control, this happens because of a weakened immune system and the outcome is cancer.

I found it interesting to note that this "per embryonic" state seems to coincide with the trophoblastic theory of cancer postulated in "world without cancer" In that book they did not understand how it came about but had a good explanation  of the mechanism of cancer itself.


This is a thesis on how pregnancy and cancer are related
http://www.worldwithoutcancer.org.uk/thesis.html


I recommend Nancy Bank's book, it's very informative and shatters yet another lie, the Aids lie, to pieces.

John

[Free Truth]

G. Edward Griffin - A World Without Cancer - The Story Of Vitamin B17:

http://video.google.com/videoplay?docid ... 281243507#

When eating apples, peaches, pears, plums and cherries also, crack open and/or skin the seed and eat what is inside! Vitamin B-17, baby.

[CrackSmokeRepublican]

Von Ardenne's research is interesting and ties with the Italian researcher's findings on "White" Cancer as a fungus.  Again, lactate and supplied by thin capillaries is the source of "supply" for the abnormal growth. --CSR

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Physicist Manfred Von Ardenne's Hyperthermia Treatment

http://www.aliciapatterson.org/APF00197 ... vik08.html

One of the more intriguing aspects of von Ardenne's work in cancer is that it bears some resemblance to his work on the atomic bomb. His attack on cancer brings into play a unique biological chain reaction which reminds one of the chain reaction so critical to the explosion of a nuclear device. And as in the detonation of a bomb, von Ardenne's biological bomb can also be triggered by a burst of X-radiation.

But let us start at the beginning.

The German assault on cancer takes advantage of three ways in which solid tumors differ significantly from normal tissue: 1) Tumors have sluggish bloodflow; 2) to make energy, they rely heavily upon "fermentation" rather than respiration; 3) they have elevated levels of an enzyme called beta-glucuronidase. These differences, respectively, make tumors selectively vulnerable to attack by heat therapy (hyperthermia) acidification an enzymatic destruction. In combination, these differences synergize that vulnerability in a most remarkable and explosive fashion.

Let's look first at the inhibited blood flow through tumors and understand how this chink in cancer's armor can be exploited without destructive side effects. Unlike normal tissues, cancers are supplied almost exclusively by capillaries, those tiny blood vessels that complement veins and arteries in healthy tissue. These small vessels, many of them only large enough to accommodate a parade of blood cells marching in single file, provide considerable resistance to the onrush of blood from outside the tumor. It has been reliably estimated that, generally, blood flow through tumors is only two to fifteen percent that of normal tissue. This is a significant difference — and one that has profound implications in terms of "substrate supply" to the tumor and heat dissipation within the tumor.

Here a slight digression is in order to explain, in part, why the standard, prevailing anti-cancer therapies so often fail. The capillary vascularization of the tumor mass has a lot to do with that failure — even as it contributes to the success of hyperthermia and the East German assault. Stagnant blood flow minimizes the amount of drugs that can penetrate the tumor and attack the cancer cells. But these chemotherapies, which are all cell poisons, have little difficulty in reaching the rest of the body, with its normal vascularization. It is true that they are designed, in a sense, to be selective. But the degree of selectivity is limited. Cells are most vulnerable to attack while undergoing division — and particularly certain stages of division. Cancer cells are rapidly dividing and so, theoretically, at least, provide a good target for cytotoxic drugs. Unfortunately, the precursors of the cells that are the frontline soldiers in our natural, immunological defense systems, are also rapidly dividing and provide equally good targets — better, in fact, because they are not shielded by poor vascularization. Chemotherapeutic agents reach them easily.

There are still other problems. Some tumor cells, because of sluggish blood flow, get so little oxygen and other necessary "substrate" supplies that they stop cycling and go, in effect, into a state of temporary suspension where they are largely immune to the anti-mitotic (cell-division) chemotherapies. They form a malignant core from which trouble can — and will — arise again. As for radiation, it, too, is very likely to be more destructive of the body's immune cells than of cancer. It is well established that cancers exhibit "hypoxic radioresistance": X-radiation needs oxygen to be optimally effective. So once again that poor vascularization serves cancer well. Even when radiation and chemotherapies succeed in dissolving some of the cancer mass, cancer antigens (those little proteins that tip off the body that a foreign invader is present) attached to the tumor debris flood through the body, including the lymph nodes (factories for the body's immune surveillance and attack systems). The immune factories then respond by producing (through cell division) massive numbers of defensive cells designed to inactivate the invaders. This mitotic response immediately puts the immune system in the same danger as the cancer cells: destruction by chemotherapies (and/or radiation) which singlemindedly take advantage of cell-cycle rate differences.

So all too often we gain an inch and lose a mile.

The same peculiarities of the body — and of cancer — that previously contributed to our defeat, however, may now be used to help us succeed. As McCarty comments: "Rather than basing therapeutic selectivity on cell-cycle rate differences, a promising alternative approach is to use stagnant tumor blood flow and depressed substrate levels as a point of therapeutic attack."

And so back to hyperthermia. Heat will kill tissue — both normal and cancerous, but it will kill those tissues in which there is stagnant blood flow first. The body, after all, is not so different from an engine, the various parts of which will not overheat and be destroyed so long as an ample flow of water or other coolant circulates through passages within the engine block, carrying off heat generated by the combustion of fuel within the cylinders. Tumors are engines with a coolant supply insufficient to cope with temperatures not too much above that which normally exist within the body, temperatures which, felicitously, leave normal tissues, with their more adequate coolant supply, largely unscathed. The safety margin is widened further by the fact that many cancers, independent of the vascularization issue, perish at temperatures lower than those necessary for the destruction of normal tissue; why this is, no one knows.
Hyperthermia in the U.S.: Remarkable Results

The American Cancer Society was already trying to discourage anyone from investigating hyperthermia (high-temperature therapy) several years ago, citing Manfred von Ardenne as the principal practitioner of this "unproven" idea. Fortunately, MvA paid the ACS no heed, and neither did several researchers in this country who have now come forward with extremely promising results. The field looks so promising in fact that the ACS was recently pressured, by some very orthodox individuals, I have learned, into removing from its "Unproven" list the so-called "Coley Toxins" developed by the late W. B. Coley, M.D. These toxins, consisting of various infectious agents, apparently brought about striking remissions in several advanced cancer patients. They constituted, many now believe, an early form of whole-body hyperthermia, which may have worked not so much by directly killing cancer cells through heat but by stimulating the body's overall immune-response systems. There is evidence that generalized (whole-body) hyperthermia can do that.

Indeed, there is fascinating speculation now that this sort of whole-body heat effect may be responsible, at least in part (dietary factors are certainly also important), for the lower incidence of cancers of the breast, penis, testis and skin in Japan. In a land essentially without central heating, the Japanese, over the centuries, have learned to love and rely upon daily — and sometimes twice daily — baths in special tubs that leave them immersed to the neck. These are extremely hot baths, meant to have a lingering effect, and they are indulged in for long periods of times. The water temperature is amazingly hot — 42-48 degrees C. or 110 to 120 degrees F. Investigators have found that such bathing often produces rectal temperatures of 104 degrees F.

Commenting on this phenomenon in an address delivered to the International Conference on Hyperthermia and Radiation in Washington D.C., not long ago, Helen Coley Nauts, daughter of the late Dr. Coley and executive director of the Cancer Research Institute in New York (the medical director of which is Dr. Lloyd Old, vice president of Sloan-Kettering), noted that "in Finland, where very hot sauna bathing is practiced, the incidence of testicular and breast cancer is also lower than in neighboring countries where the sauna is not used. The end results in Finland following lumpectomy and relatively low doses of irradiation for breast cancer are markedly better than in other countries using more radical surgery and radiation."

All of this, as I note, remains speculative. Controlled experiments in the United States, however, demonstrate that heat, quite clearly, can kill cancer while sparing normal tissue. Writing in the Journal of the American Medical Association (May 17, 1976), Harry H. LeVeen, M.D., and colleagues from the department of surgery, Veterans Administration Hospital, Downstate (NY) Medical Center and State University of New York, Brooklyn, reported on the response of 21 cancer patients to hyperthermia. In their article, called "Tumor Eradication by Radiofrequency Therapy," the New York researchers reported that they were able to shrink or completely eradicate a variety of tumors in most of the 21 patients after exposing their growths to heat-producing electromagnetic waves at a frequency of 13-56 megahertz (13-56 million cycles per second).

Electrodes are placed on either side of the tumor (e.g., on either side of the chest wall in the case of lung tumors) and energy pulsed between them. Only in the tumor itself, with its inefficient blood flow, do the temperatures reach significant, destructive levels. This sort of "local," as opposed to "whole-body," hyperthermia, is thus aimed directly at the tumor. So far it has been effective against solid tumors of a wide variety, including those of the lungs, kidneys, neck, head and intestines. It is not effective against leukemias and other widely disseminated cancers, although whole-body hyperthermia may be of some benefit even in those categories.

The number of heat treatments needed to destroy a tumor varies from patient to patient; each treatment usually lasts 30 to 45 minutes. In many cases, the heat treatment does not totally destroy the tumor but shrinks it sufficiently that it can be safely and effectively removed by surgery. It is not a cancer "cure" in and of itself because it does not, so far as anyone knows, correct the fundamental problems that gave rise to the cancer in the first place or allowed it to take hold. But since it is apparently devoid of serious side effects and since it does not suppress the body's immune-response systems (and, indeed, especially in the case of whole-body hyperthermia, may actually enhance them) it appears to be a very significant step forward and a substantial advance over radiation and chemotherapy.

Other researchers, at the Animal Resource Facility of the University of New Mexico School of Medicine, using what they call localized current field hyperthermy (emitting at 500 kHz), say they are effecting complete tumor eradication in about one-third of their cancerous test animals. Another third experience partial tumor regression; the final third evince no change. And another group in New Mexico, also affiliated with a VA hospital, has reported significant shrinkage of tumors in 14 of 20 advanced cancer patients brought about by a combination of hyperthermia and chemotherapy. In this instance, whole-body hyperthermia, was induced by wrapping patients in hot-water-heated blankets and by circulating hot gas through tubes inserted into the lungs. The results, the researchers conclude, were much better than could have been expected through the use of chemotherapy alone.

The Lysosomal Cytolytic Chain Reaction
(Delivering the Coup de Grace)

Apart from all the other beneficial effects of hyperthermia, there is yet another factor that it brings into play — one that is central to Manfred von Ardenne's unique approach to combating cancer. To understand this additional factor, let us move on to the second way in which cancerous tissues differ from normal tissues: they derive energy through the fermentation of glucose rather than through oxygen respiration. The end product of all this is lactic acid. As the lactate accumulates in the tumor, its pH falls, that is, it becomes acidified. Cancerous tissues are thus more acidic than normal tissues. Manfred von Ardenne recognized some years ago that tumor acidity might be used quite effectively to help destroy the tumor and he quickly devised ways of making tumors even more acidic than they normally are. One way to do this is to give the tumor all the glucose it wants in order to boost lactic acid production. This can be achieved by inducing hyperglycemia in cancer patients through glucose infusion which continues for many hours, during the course of treatment.

Heavy Vitamin-A therapy with Dr. Livingstone.  

The Absisic Acid / Vitamin A / Apricot Kernel Connection

Dr. Livingstone's second recent discovery involves a substance that appears capable of either halting microbial HCG production or of neutralizing the HCG once it has been produced. And, again, there is a substantial coincidence in evidence here, for the substance in question, though unrelated to amygdalin in terms of chemical structure, is also contained in high concentrations in apricot kernels and most of the other natural sources rich in amygdalin! The substance is called absisic acid.

Because of its fungal, almost plant-like characteristics, cryptocides might be vulnerable to attack, Dr. Livingstone reasoned, by various plant hormones. From her botanical studies she knew about the plant hormones known as "dormans" (from whence comes the word "dormancy") that keep seeds from sprouting in the wintertime. Again, Dr. Livingstone thought of laetrile, derived primarily from apricot kernels. Surely, she thought, apricot seeds must contain one of the dormans. Further study revealed that absisic acid, which is one of the dormans, is present in apricot kernels in high concentrations.

Dr. Livingstone was further encouraged by news just then issuing out of the National Cancer Institute that a substance called retinoic acid was showing indications, in animal tests, of being a potent cancer inhibitor and possibly very effective cancer preventive, at least in some categories. Dr. Livingstone knew that absisic acid is closely related to retinoic acid, that both are vitamin A analogues. A great many seemingly disparate threads suddenly seemed to be coinciding. Some further sleuthing revealed that the "wheat-grass" cancer control that has been so long decried as quackery might have some rational basis, after all, because Dr. Livingstone found that wheat grass is one of the richest sources of absisic acid.

By this time the San Diego researcher had more than enough data to convince her to begin testing absisic acid on animals with cancer. Unfortunately, purified absisic acid currently sells for $70,000 a pound. (Costs will go down when/if the stuff is mass produced.) Still, she was able to get enough to do studies on some 1,500 test animals. Some of this work is still going on. A preliminary analysis indicates that if you give the substance to animals that spontaneously develop tumors you get a 40 percent reduction in the overall weight of the tumors (as compared to controls). If you give absisic acid and the cryptocides vaccines to the same type of animal, Dr. Livingstone says, you can nearly obliterate the tumors (of this particular type), reducing them by better than 90 percent. More definitive figures must await the conclusion of testing.

In vitro tests confirmed that cryptocides, exposed to absisic acid, stops making HCG.

Because of the expense of refined absisic acid, Dr. Livingstone indicates she will, for the time being anyway, prescribe diets that are naturally rich in the substance — wheat grass juices, sprouting grains of all kinds, possibly apricot and peach kernels.

Because absisic acid is obtainable from apricot kernels some are now claiming that it is this substance and not amygdalin that is fighting cancer. This is misleading, however, because in the manufacture of amygdalin from apricot kernels most, if not all, of the absisic acid is lost. It would appear that apricot kernels may contain two potentially powerful anti-cancer substances — amygdalin and absisic acidd. One might expect, then, that apricot kernels might actually be more useful against cancer than amygdalin alone. Andrew McNaughton is one chief backer of laetrile (see DMR-4) who is quick to concede this possibility. He recalls one period in which there was a shortage of refined amygdalin and laetrile patients had to rely, instead, on large numbers of apricot kernels.

"It was my impression — and that of some others — that these patients actually did better than patients who get the pure stuff." He plans to follow-up on this possibility.

It is fortunate that the NCI has begun to grasp the anti-cancer potential of vitamin A and its analogues. Dr. Livingstone's work may give other researchers a handle on the reasons why these substances may be so effective. If they would seriously examine her work they might also discover a common point at which a great many cancers could be effectively attacked — the cryptocides. It should be noted, in this regard, however, that Virginia Livingstone does not claim that this micro-organism is the unitary cause of cancer. She recognizes that cancer has many origins — ranging from environmental pollutants to stress. But all of these diverse factors, she believes, weaken the body's defenses to the point where cryptocides, generally held in check by a healthy immune system, runs rampant, produces HCG and confers immunity on cells made cancerous by extraneous factors.
The Vitamin A Evidence

Vitamin A work in cancer goes back some years. Typically, it has taken NCI more than a decade to followup on what must certainly have been one of the most significant findings of all time in cancer research. In October of 1966, at the Ninth International Cancer Congress in Tokyo, Dr. Umberto Saffiotti, a pathologist at the Chicago Medical School, reported that he had first induced lung cancer in nearly 100 percent of his test animals (hampsters) and then, by administering vitamin A, achieved significant reversals of those cancers. He chose vitamin A because it is known to be important in maintaining healthy respiratory membranes. When he gave large doses of the vitamin, along with doses of the carcinogen he was using to induce cancer, few of the animals developed cancer — eventhough the carcinogen dose was the same that had induced cancers in nearly 100 percent of the animals who received no simultaneous vitamin A.

Dr. Saffiotti warned that his results, though very dramatic, were preliminary and that there could be some danger to humans in taking very large doses of vitamin A. The amount of vitamin A that most of us can safely tolerate, however, is now widely believed to be well above that which is needed, at least in terms of using vitamin A as a partial cancer preventive. Many well-informed nutritional texts now recommend daily doses of 20,000 International Units daily. The authoritative Merck Manual, used by doctors, observes that "with one possible exception, this rare condition [hypervitaminosis A] thus far has been described only in patients receiving more than 100,000 units a day." In any event, the symptoms of hypervitaminosis A become quickly apparent — dry rough skin, cracked lips and coarse hair followed by severe heachache and generalized weakness — and are quickly reversed upon lowering the vitamin A dose. Persons who smoke heavily and are exposed to smog and other pollutants are particularly likely to need large doses of vitamin A.

But back to Dr. Saffiotti. What became of him and his promising work? Actually, I touched upon this episode in a "Short Take" in DMR-2 — nearly a year ago. I noted that Harold J. Taub in his excellent book, Keeping Healthy in a Polluted World (Harper & Row, 1974, Penguin Books, 1975), covered Saffiotti's early work. After Taub's description of that work there appeared this unintentionally melancholy paragraph: "After this work was done, Dr. Saffiotti was appointed to an important post at the National Cancer Institute and is now working there in Bethesda, Maryland. Although there is little doubt he is pursuing his studies of vitamin A as a cancer preventive, no public information about his work has been issued since he moved to Bethesda." No information for nearly ten years. Right. In fact, the public didn't hear much of anything of Dr. Saffiotti again until April, 1976 when he announced he was resigning as head of the NCI division that investigates and tries to identify cancer causing agents so that they can be banned or preventive measures taken against them. He resigned, he said, in protest over lack-of-support-for and mismanagement of the program from higher up the NCI chain-of-command.

Saffiotti is gone (maybe now he can get back to his vitamin A work) but some others at NCI have expressed interest in the vitamin, eventhough the agency has dragged its feet on funding any research in the area. (Apparently some.trials will get underway next fall.) When Dr. Eli Seifter, a very distinguished scientist, went to NCI with his promising vitamin A leads his requests for funds were rejected. This isn't surprising, of course, since the NCI, despite its nearly billion in funding each year, invested only a few million in nutritional cancer research last year — and even that pittance had to be squeezed out of the agency by Congressional mandate. This year, shockingly, after all the talk and all the lip service in recognition of dietary factors in cancer, there is, I am reliably informed, absolute no money whatever available to fund new diet/cancer projects. But there's still plenty going into the virus program, which damn near everybody agrees is worthless.

Considerable new data on vitamin A efficacy has been forthcoming recently from Vanderbilt University, Massachusetts Institute of Technology and the Hoffman-LaRoche Research Laboratory in Basel, Switzerland. Vitamin A has shown favorable results in cancers of the lungs, rectum, skin, trachea, digestive system and breasts. One MIT professor of nutritional chemistry estimates "that about 30 percent of the American public suffers from some degree of vitamin A deficiency, early symptoms of which include a loss of smell and taste, a dryness of the skin and the mucous linings of the nose and throat."

Dr. Michael B. Sporn, chief of the lung cancer division of NCI, is particularly interested in the possible use of large doses of synthetic vitamin A analogues (without high dose toxicity associated with natural vitamin A) for use against lung cancer — both as treatment and preventive. One of the retinoic acids looks particularly promising.

Experts are still at a loss to explain exactly how vitamin A acts against cancer. Some have suggested that it inhibits enzymes that are necessary for some chemicals to become carcinogenic. But vitamin A has been shown to be effective even against chemical carcinogens that definitely do not require enzymatic activation. Others are now suggesting that it may work by stimulating the body's immune responses against cancer. Support for this idea comes from research showing that BCG, another stimulant of the body's anti-cancer mechanisms, is potentiated (one-hundredfold in one experiment) when given in conjunction with a vitamin A derivative.

It is surely time now for the NCI — and others — to consider the possible role Progenitor cryptocides might play in this intriguing puzzle.
Afterword: Vitamin A and the Gerson Diet

While they are at it, the NCI might profitably take another look-indeed, a first look — at the Gerson diet. Albert Schweitzer credited Dr. Max Gerson with saving his wife's life and described him as "a medical genius who walked among us." Dr. Gerson presented voluminous data in support of his contention that his dietary regimen was very effective against a wide range of cancers. Yet, Gerson, whose credentials were excellent, was maligned as a fraud by the New York County Medical Society and others in he medical establishment who never bothered to investigate his work firsthand. In addition to the diet, which was as rigorous in terms of what one had to avoid as what one had to eat, Gerson insisted upon a variety of treatments designed to cleanse the bowels and some of the other organs of accumulated wastes. In general, his therapies seemed to enhance the overall well-being of the patient so that he/she could better cope with the cancer. It seems likely that the diet was efficacious, if for no other reason than (as a recent analysis carried out by medical students at Hahnemann Medical College, the University of Massachusets and Boston University has revealed) it delivers at least 100,000 IUs of vitamin A daily to the body. Additionally, the diet delivers an extraordinary one to two grams of vitamin C daily. This is "extraordinary" at least by comparison with the typical, vitamin C deficient diet of most Americans. And as reported in DMR-7, vitamin C (as demonstrated by Dr. Pauling and now also by a researcher at NCI) has an immunostimulant effect.

It's amazing — and wonderful — how these things seem to be pulling together in a sense: Vitamins A and C, the vitamin A analogues, such as retinoic acid and absisic acid, apricot kernels, wheat grass, BCG and other vaccines, such as those pioneered by Dr. Livingstone, and, last but not least, perhaps that most mysterious of bugs, Progenitor cryptocides