Possible Cancer Cure. A Marijuana/Cannabis Oil Story - A film by David Triplett - Reupload

[ahaze]

Great documentary, a must-see imo.Thanks for posting /Tab.

Bit ironic that the uploader's name is ''Legalizeisrael", when the jew-pharmaceutical industry and jew-petrochemical industry are the main reasons for the present legislation involving cannabis.

 It's good to see the public record growing with such explicitly noteworthy documentaries.  I'm impressed at how focused this REAL Cure series of vids is.  Another worth noting here is The Union: The Business Behind Getting High which covers the pharmaceutical aspects this REAL Cure series provides (though not quite as much in depth) and provides a more comprehensive overview of the socio-political-economic impacts beyond all the health tragedies the prohibition induces (plus good soundtrack, humor and eye opening features).  

_http://topdocumentaryfilms.com/the-union-the-business-behind-getting-high/
The Union: The Business Behind Getting High

Ever wonder what British Columbia's most profitable industries are? Logging? Fishing? Tourism? Ever think to include marijuana? If you haven't, think again. No longer a hobby for the stereotypical hippie culture of the '60s, BC's illegal marijuana trade industry has evolved into a seemingly unstoppable business giant, dubbed by those involved as 'The Union'.

Commanding upwards of $7 billion Canadian annually, The Union's roots stretch far and wide, directly and indirectly affecting all areas of our society. With 65% to 85% of all 'BC Bud' being exported to the United States, it's clear that the BC marijuana trade has become an international issue with consequences that extend far beyond our borders. When there are record profits to be made, who are the players, and when do their motives become questionable?

Why is marijuana illegal? What health risks do we really face? Does prohabition work? What would happen if we taxed it? Medicine, paper, fuel, textiles, food, etc. Are we missing something here?

Follow filmmaker Adam Scorgie as he dives head first into Canada's most socially acceptable illegal activity. Along the way, Adam demsytifies the underground market and brings to light how such a large industry can function while remaining illegal. By interviewing experts from around the globe, including growers, clippers, police officers, criminalogists, economists, psychologists, medical doctors, politicians and pop culture icons, Scorgie explores the cause and effect nature of the business behind getting high.

Nobody's innocent in this exploration of an industry that may be profiting more by being illegal. Join Adam Scorgie as he unravels the mystery of The Union. (Excerpt from theunionmovie.com)

[/tab]

Great documentary, a must-see imo.Thanks for posting /Tab.

Bit ironic that the uploader's name is ''Legalizeisrael", when the jew-pharmaceutical industry and jew-petrochemical industry are the main reasons for the present legislation involving cannabis.

Yes! and expect some more coming for sure! When the cat seems been getting out of the bag with the healing factors in matter, they are gonna be claiming here and there authority, leadership,



usurping and "carrying the flag" sheparding the näive goyim




when in reality, business as usual


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[/tab]

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Dad Gave Infant Son Battling Brain Cancer & Chemo Medical Marijuana that CURED Him!

[youtube:1ai6x9jq]http://www.youtube.com/watch?v=2Kd3kR-4tB8[/youtube]1ai6x9jq]


My journey with cancer-rick simpson oil


[youtube:1ai6x9jq]http://www.youtube.com/watch?v=d4_L8n-1dAE[/youtube]1ai6x9jq]


[youtube:1ai6x9jq]http://www.youtube.com/watch?v=srE1EA0FVSc[/youtube]1ai6x9jq]


http://www.youtube.com/user/AIrishsurvivor


Tommy Chong giving Rick Simpson, Phoenix Tears and Run From The Cure a shout out.

[youtube:1ai6x9jq]http://www.youtube.com/watch?v=9v1xxEbP1y8[/youtube]1ai6x9jq]

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[/tab]

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Vitamin Cannabis 6 "The Perfect Corporation"

[youtube:kw4exr4e]http://www.youtube.com/watch?v=CIjG_AbxudE[/youtube]kw4exr4e]

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[pas]

Thanks /tab, great video's.
Especially the little child that was cured.Awesome, and i wasn't even really surprised.

I hope this Irishsurvivor also has a succes story to tell in a while.
Only for his first dose he took far too much oil, it's not dangerous or something but it's enough to put an elephant to sleep.
Pretty funny, i hope he handled his high a bit.

[youtube:1m18puyo]http://www.youtube.com/watch?v=srE1EA0FVSc[/youtube]1m18puyo]

[ahaze]

_http://www.marketwire.com/press-release/medical-marijuana-inc-announces-major-deal-distribute-three-beverages-with-new-hemp-pinksheets-mjna-1514700.htm
SOURCE: Medical Marijuana Inc

May 16, 2011 08:50 ET
Medical Marijuana Inc Announces Major Deal to Distribute Three Beverages With New Hemp and Cannabis Extract Technology From CannaBANK Inc.



SAN DIEGO, CA--(Marketwire - May 16, 2011) - Medical Marijuana Inc is proud to announce that CannaBANK™'s patent pending CBD (Cannabidiol) extraction process will allow for direct infusion of the health and wellness benefits providing CBD's into three new bottled water enhanced beverages. This technology will be used by Medical Marijuana Inc (PINKSHEETS: MJNA) to bottle and distribute these beverages in the world beverage marketplace. Medical Marijuana Inc is reviewing several bids for the distribution rights in Latin America as well as the United States. Bottled drinking water market alone exceeds 8.7 billion gallons (wholesale market $11.2 billion) in the USA and is close approaching the Carbonated Soft Drink market in terms of annual sales. Source: _www.bottledwater.org (2008 figures).

CBD-infused water will have all the advantages of traditional pure spring water plus the added health and wellness benefits of CBD. The beverages will be marketed throughout similar distribution channels as bottled drinking water at retail and grocery outlets, so as to be readily available to the general populace in the next few months.

CBD is an extract from cannabis and contains none of the psycho-active ingredients of marijuana, known as THC. CBD has been well studied by major University Medical Research Schools in the United States. One CBD benefit is to reduce DNA damage due to free radical species, anti-aging of neural, CNS, COPD, and other cellular targets. This is described in the United States Health Department Patent # 6,630,507 titled "Cannabis as Antioxidants and Neuroprotectants" (see _http://tinyurl.com/6hwwmt) as well as many other research articles published in scientific journals.

Dr. Donald Abrahms, chief of Hematology and Oncology from the University of California at San Francisco, has been researching CBD health benefits for many years and more research is available via the following YouTube link: _http://www.youtube.com/watch?v=IHBsxfbgrbY

Aside from Dr Abrahms work, research by the US Government and other top US University Medical Research departments have shown CBD to carry significant benefits. CBD has shown positive as described in the United States Health Department Patent # 6,630,507 results with Parkinson's disease, HIV, Down's Syndrome, Crohn's disease, Rheumatoid Arthritis, Diabetes, Post Heart Operation and Heart patients, including high blood pressure, Alzheimer's and many other conditions. CBD has been shown to be a natural T-cell enhancer.

Three products are currently available from Medical Marijuana Inc's enhanced drinking water beverage line:

CBD-infused water, which has all of the medical benefits of CBD.
 THC-free water, which has all of the additional 500 plus natural benefits less THC.
 Hemp water, which uses all the direct benefits of hemp extracts.

Medical Marijuana Inc has several additional beneficial beverage lines which will be launched over the next several months.

ABOUT MEDICAL MARIJUANA INC

Our mission is to be the world's premier cannabis and hemp industry innovators, leveraging our team of professionals to source, evaluate, invest in and purchase value-added sustainable companies, while allowing them to keep their integrity and entrepreneurial spirit. We strive to create awareness within our industry, pay homage to the visionaries and activists of the past and present, provide the platform from which the industry can emerge into a global sustainable economy for all. Medical Marijuana Inc recognizes the vast and unequaled opportunities that exist in the rapidly expanding hemp and medical marijuana industries. The scientific recognition of cannabis has brought legalized marijuana use to the forefront of mainstream discussion, thus opening the door for safe and lucrative investment opportunities.

ABOUT CANNABANK

CannaBANK's mission is to help create a sustainable economy which in turn helps create a sustainable planet offering health and economic freedom through education and awareness.

CannaBANK™ and the CannaBANK™ logo are registered trademarks of Hemp Deposit & Distribution Corp. (HDDC), d/b/a CannaBANK, Inc. in the U.S. and certain other countries. All other trademarks mentioned in this document are the property of their respective owners. The use of the word "partner" does not imply a partner relationship between CannaBANK and any other company.

FORWARD-LOOKING DISCLAIMER

This press release may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties and other factors, which may cause the actual results, performance or achievements of Medical Marijuana, Inc. to be materially different from the statements made herein.

The Science of Medical Cannabis: A Conversation with Donald Abrams, M.D.
[youtube:1omlpt35]http://www.youtube.com/watch?v=IHBsxfbgrbY[/youtube]1omlpt35]

'...it's all about the politics and not the science.' :problem:

[CrackSmokeRepublican]

A lot of cancers deal lactate and lactic acid. It is basically food for cancers to grow with if not balanced in the body.
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Sunday, 21 September 2008 23:49 UK

How gut bugs could trigger cancer

Enterococcus faecalis

Scientists have uncovered a chain reaction which could link a type of bacterium living in our intestines to the development of colon cancer.

Enterococcus faecalis is harmless in the vast majority of people, but US scientists have found that it can produce harmful chemicals.

The Journal of Medical Microbiology study found these can damage DNA, and prompt gene activity linked to cancer.

A UK expert said it was plausible that bacteria could cause colon cancer.

However, he stressed that E.faecalis was very unlikely to be the only bacterium which had such an effect.

   
This research puts into perspective the complexity of the effects normal gut bacteria can have on the health of the individual
Professor Mark Huycke
Researcher

Our guts provide a home to dozens of different types of bacteria, many of which actually provide a useful service, helping break down indigestible sugars in food by fermentation, or even "training" the body's immune system.

However, in recent years, scientists have suggested that in certain, susceptible individuals, these bacteria can actually do harm.

E.faecalis, sometimes also known as Group D Streptococcus, is one of those under suspicion, and the research by the Department of Veterans Affairs Medical Center in Oklahoma City strengthens the link.

The researchers investigated how colon cells in the laboratory reacted to the presence of the bacterium, when it is in a "fermentation" state.

In this state, it produces a kind of oxygen molecule called "superoxide", and it is this which can damage DNA in surrounding cells.

Gene activity

Professor Mark Huycke, who led the research, found that the apparent effects were not limited to this.

"We found that superoxide led to strong signalling in immune cells called macrophages - it also altered the way some cells in the gut grew and divided and even increased the productivity of genes which are associated with cancer."

In total, the expression of 42 genes linked to vital processes in human cells was altered by the presence of E. faecalis in this state.

"This research puts into perspective the complexity of the effects normal gut bacteria can have on the health of the individual."

Dr Barry Campbell, a gut microbiology researcher from the University of Liverpool, agreed that E.faecalis was a candidate for cancerous changes.

However, he said that other bowel bacteria could also be behind the cell changes which eventually lead to tumours.

He said: "There is not going to be only one culprit. Our own team is interested in a particular type of E.coli with this in mind.

"There are also many other factors which are involved, such as genetics and environment."

Professor Ian Rowland, a specialist in gut bacteria from Reading University, said: "This shows how it could happen, although whether this actually does happen in a human is another matter.

"There is a lot of circumstantial evidence that gut bacteria are important in colorectal cancer, although we don't fully understand why.

"In the case of Enterococcus faecalis, we know that most people have this in their gut, but most people don't get colon cancer, so there must be other factors involved."

http://news.bbc.co.uk/2/hi/health/7625192.stm

============

Manuka Honey for gums
 
 
Effects of Manuka Honey on Plaque and Gingivitis
By Periodontal Periodontitis Gingivitis Disease
on September 24, 2010

Effects of Manuka Honey on Plaque and Gingivitis

As we all know, honey is sweet and good for our health. There is yet another kind of honey known as Manuka honey. It has many more advantages than a regular honey.

It contains antibacterial properties to reduce some health problems. It contains properties known as Unique Manuka Factor or (UMF). This antibacterial factor is unaffected by bacteria in our body and also destroys the hydrogen peroxide components. Up to this day, findings still shows that no bacteria can overcome it.

In a recent study, Manuka honey with antibacterial properties that rated (UMF) 15 can be used to prevent plaques and gingivitis. They even experimented to put the components of these Manuka honey as the ingredients of a chewing gum, and it worked very well. It has reduced the bleeding of gums by 50%. Manuka honey can only be found in New Zealand hiding in Manuka bush, which was discovered by a group of medical professionals. The (UMF) is now compared to phenol (a standard antiseptic) and is now a registered trademark operating from New Zealand.

In fact, the medical investigative group has thirty volunteers from a certain University as participants in the study. They checked each and everyone's teeth to be qualified to the test. To be exact, they should have at least 20 natural teeth with measurable plaque evident. The study was a success. The study shows that the components of the Manuka honey can reduce plaques and gingivitis.

It has shown to be more effective than other honeys against Helieohacler pylori (A Gram-negative, microaerophilic bacterium that can inhabit various areas of the stomach, particularly the antrum), enterococci (a genus of lactic acid bacteria of the phylum Firmicutes), Staphylococcus aureus (a facultatively anaerobic, gram-positive coccus and is the most common cause of staph infections), and Escherichia coli (Gram negative rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms).

http://www.periodontal-periodontitis-gi ... y-for-gums


==========

Some evidence below showing Cannabinoids and THC act as regulator for Lactate production in cells.

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In vitro effects of psychoactive and non-psychoactive cannabinoids on immature rat Sertoli cell function.
Newton SC, Murphy LL, Bartke A.
Source

Department of Physiology, Southern Illinois University, School of Medicine, Carbondale 62901.
Abstract

We have examined the effects of psychoactive and non-psychoactive cannabinoids on isolated immature rat Sertoli cells cultured in either serum-free or serum-containing media. Lactate accumulation by Sertoli cells in serum-free control cultures was 10 fold greater than the values obtained in control cultures exposed to serum. Under either culture condition, 3.1 micrograms/ml of delta-9-tetrahydrocannabinol (THC) or cannabinol (CBN) stimulated lactate secretion above control levels. Cannabidiol (CBD) stimulated lactate secretion in serum-containing but not in serum-free media. Using serum-free culture conditions, we next studied the in vitro effects of combinations of THC and either epinephrine or FSH on lactate and transferrin secretion by immature rat Sertoli cells. Co-incubation of 0.1 microM epinephrine with 0.8 or 3.1 microgram/ml THC significantly stimulated lactate secretion when compared to epinephrine or THC alone, while only the high THC dose increased transferrin secretion. Moreover, co-incubation of FSH (1 micrograms/ml) with THC (0.8 or 3.1 micrograms/ml), significantly stimulated both lactate and transferrin production by immature rat Sertoli cells. These results add to the growing evidence that cannabinoids can exert direct effects on Sertoli cell function and modulate their responses to physiological stimuli.

http://www.ncbi.nlm.nih.gov/pubmed/8231631

====

Drugs for lactate and cancer control:
http://hopes.stanford.edu/n3625/drugs-s ... energy-met

[CrackSmokeRepublican]

Interesting that pot reduces inflammation...via  beta-carophyllene which in turn starves cancers of fuel sources.

-----------
Simple Sugar, Lactate, Is Like 'Candy for Cancer Cells': Cancer Cells Accelerate Aging and Inflammation in the Body to Drive Tumor Growth


ScienceDaily (May 26, 2011) — Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow -- and how to make it stop. Interestingly, cancer cells accelerate the aging of nearby connective tissue cells to cause inflammation, which ultimately provides "fuel" for the tumor to grow and even metastasize.

This revealing symbiotic process, which is similar to how muscle and brain cells communicate with the body, could prove useful for developing new drugs to prevent and treat cancers. In this simple model, our bodies provide nourishment for the cancer cells, via chronic inflammation.

"People think that inflammation drives cancer, but they never understood the mechanism," said Michael P. Lisanti, M.D., Ph.D., Professor and Chair of Stem Cell Biology & Regenerative Medicine at Jefferson Medical College of Thomas Jefferson University and a member of the Kimmel Cancer Center. "What we found is that cancer cells are accelerating aging and inflammation, which is making high-energy nutrients to feed cancer cells."

In normal aging, DNA is damaged and the body begins to deteriorate because of oxidative stress. "We are all slowly rusting, like the Tin-man in the Wizard of Oz," Dr. Lisanti said. "And there is a very similar process going on in the tumor's local environment." Interestingly, cancer cells induce "oxidative stress," the rusting process, in normal connective tissue, in order to extract vital nutrients.

Dr. Lisanti and his team previously discovered that cancer cells induce this type of stress response (autophagy) in nearby cells, to feed themselves and grow. However, the mechanism by which the cancer cells induce this stress and, more importantly, the relationship between the connective tissue and how this "energy" is transferred was unclear.

"Nobody fully understands the link between aging and cancer," said Dr. Lisanti, who used pre-clinical models, as well as tumors from breast cancer patients, to study these mechanisms. "What we see now is that as you age, your whole body becomes more sensitive to this parasitic cancer mechanism, and the cancer cells selectively accelerate the aging process via inflammation in the connective tissue."

This helps explain why cancers exist in people of all ages, but susceptibility increases as you age. If aggressive enough, cancer cells can induce accelerated aging in the tumor, regardless of age, to speed up the process.

The researchers' findings are being published online June 1st in the journal Cell Cycle in three separate papers.

One paper analyzes the gene profiles of the laser-captured connective tissue, associated with lethal tumors, in human breast cancer patients. In this paper, lethal cancers show the same gene expression pattern associated with normal aging, as well as Alzheimer's disease. In fact, these aging and Alzheimer's disease signatures can identify which breast cancer patients will undergo metastasis. The researchers find that oxidative stress is a common "driver" for both dementia and cancer cell spreading.

In another study, the researchers explain that cancer cells initiate a "lactate shuttle" to move lactate -- the "food" -- from the connective tissue to the cancer cells. There's a transporter that is "spilling" lactate from the connective tissue and a transporter that then "gobbles" it up in the cancer cells."

The implication is that the fibroblasts in the connective tissue are feeding cancer cells directly via pumps, called MCT1 and MCT4, or mono-carboxylate transporters. The researchers see that lactate is like "candy" for cancer cells. And cancer cells are addicted to this supply of "candy."

"We've essentially shown for the first time that there is lactate shuttle in human tumors," said Dr. Lisanti. "It was first discovered nearly 100 years ago in muscles, 15 years ago in the brain, and now we've shown this shuttle also exists in human tumors."

It's all the same mechanism, where one cell type literally "feeds" the other. The cancer cells are the "Queen Bees," and the connective tissue cells are the "Worker Bees." In this analogy, the "Queen Bees" use aging and inflammation as the signal to tell the "Worker Bees" to make more food.

Researchers also identified MCT4 as a biomarker for oxidative stress in cancer-associated fibroblasts, and inhibiting it could be a powerful new anti-cancer therapy.

"If lethal cancer is a disease of "accelerated aging" in the tumor's connective tissue, then cancer patients may benefit from therapy with strong antioxidants and anti-inflammatory drugs," said Dr. Lisanti. "Antioxidant therapy will "cut off the fuel supply" for cancer cells." Antioxidants also have a natural anti-inflammatory action.

http://www.sciencedaily.com/releases/20 ... 152549.htm


--------------

Why Cannabis Stems Inflammation

ScienceDaily (July 22, 200 — Cannabis has long been accredited with anti-inflammatory properties. ETH Zurich researchers, however, have now discovered that it is not only the familiar psychoactive substances that are responsible for this; a compound we take in every day in vegetable nutriment also plays a significant role.


People not only rate cannabis sativa L. highly because of its intoxicating effects; it has also long been used as a medicinal plant. Although the plant has been scrutinized for years, surprising new aspects keep cropping up. For example, researchers from ETH Zurich and Bonn University examined a component in the plant's essential oil that until then had largely been ignored and found it to have remarkable phar- macological effects. The findings open up interesting perspectives, especially for the prevention and treatment of inflammations.

Completely different molecule structure

The hemp plant contains over 450 different substances, only three of which are responsible for its intoxicating effect. They activate the two receptors in the body CB1 and CB2. Whilst the CB1 receptor in the central nervous system influences perception, the CB2 receptor in the tissue plays a crucial role in inhibiting inflammation. If the receptor is activated, the cell releases fewer pro-inflammatory signal substances, or cytokines. The scientists have now discovered that the substance beta-carophyllene, which composes between 12 and 35 percent of the cannabis plant's essential oil, activates the CB2 receptor selectively.

Unlike the three psychoactive substances, however, beta-carophyllene does not latch onto the CB1 receptor and consequently does not trigger the intoxicating effect. "Due to the various effects of cannabis, we had suspected for quite some time that other substances could come into play besides the psychoactive ones", explains Jürg Gertsch from the Institute of Pharmaceutical Sciences at ETH Zurich. "However, astonishingly we didn't know what substances these were until now."

Gertsch finds it remarkable that beta-carophyllene has a very different molecule structure to that of the classical cannabinoids. "This is presumably why no one realized that the substance can also activate the CB2 receptor." The scientists were not only able to prove that beta-carophyllene binds with the CB2 receptor in vitro but also in animal tests, where they treated mice that were suffering from an inflammatory swelling on their paws with orally administered doses of the substance. The swelling declined in up to 70 percent of the animals, even for deep doses. For mice lacking the gene for the CB2 receptor, however, the substance did not make an impact.

Common substance

The results are encouraging for the prevention or treatment of ailments in which the CB2 receptor plays a positive role. However, Gertsch explains that we are still very much in the early stages on that score. That said, the scientist can conceive that some day the compound will not only help heal certain forms of inflammation, but also be instrumental in treating chronic illnesses, such as liver cirrhosis, Morbus Crohn, osteoarthritis and arteriosclerosis. In all of these diseases, the CB2 receptor and the associated endocannabinoid system play a crucial role.
The beauty is that beta-carophyllene is not only found in cannabis but also often in plants as a whole and we consume the substance in our diet. The non-toxic compound, which incidentally has been used as a food additive for many years, can be found in spice plants like oregano, basil, cinnamon and black pepper. "Whether we have found a new link between the vegetable diet and the prevention of so-called lifestyle diseases in our study remains to be seen in future studies", adds Gertsch.
Journal reference:

    Gertsch et al. Beta-caryophyllene is a dietary cannabinoid. Proceedings of the National Academy of Sciences, 2008; 105 (26): 9099 DOI

[ahaze]

Interesting that pot reduces inflammation...via beta-carophyllene which in turn starves cancers of fuel sources.

That was one of the things that stood out to me when watching that series of vids /tab noted earlier with the post on "The REAL Cure For Cancer and Many Other Things".  The vids illustrated how increasing CBD's stimulated healthy cell growth while depriving cancer cells via the body's endocannabinoid system.   /tab's posting of those YT links proved quite timely given how recently those vids were uploaded (4/23) but then got taken down.  I took enough notes to figure out those YT 'Real Cure' vids were snapped from the film "What If Cannabis Cured Cancer".  It looks like that title's available on Amazon, and the film can be referenced at the directors site _http://lenrichmondfilms.com/
 
Plus the directors site has some helpful links including _http://www.medicalcannabis.com/  dedicated to a mission referred to as "Patients Out Of Time" and providing equally solid reference material to the "What If Cannabis Cured Cancer" film and the pieces CSR's posted here.

[ahaze]

Some research on Cannabinoids and Gliomas:

http://www.bbm1.ucm.es/cannabis/archivo ... 4-1385.pdf

Yeah, therapeutic benefit to Gliomas is mind bending in its own right, and this following article does a decent job overviewing the neuroprotective and neurogenetic stimulant properties of cannabis as well.  With this thread progressing I recollected reading this following article some time back but having discarded it back in those days as ruse info.  It took me awhile to relocate the article, and then I found it sourced back to NORML, but regardless, now finally finding it and reviewing the details I'm cursing discarding it previously as more recent news appears to be corroborating the report.  Lots of links to hard research data there on NORML's presentation of the article about the reconstructive properties of cannabis.

_http://www.norml.org/index.cfm?Group_ID=6812#comments
Cannabis and the Brain: A User's Guide
by Paul Armentano
Senior Policy Analyst
NORML | NORML Foundation•   Cannabinoids & Neurogenesis
•   Cannabis & Neuroprotection
•   Cannabinoids & Glioma
•   Cannabinoids & Neurodegeneration
•   Cannabis & Cognition


Preclinical data recently published in the Journal of Clinical Investigation demonstrating that cannabinoids may spur brain cell growth has reignited the international debate regarding the impact of marijuana on the brain. However, unlike previous pseudo-scientific campaigns that attempted to link pot smoking with a litany of cognitive abnormalities, modern research suggests what many cannabis enthusiasts have speculated all along: ganja is good for you.

Cannabinoids & Neurogenesis

"Study turns pot wisdom on its head," pronounced the Globe and Mail in October. News wires throughout North America and the world touted similar headlines -- all of which were met with a monumental silence from federal officials and law enforcement. Why all the fuss? Researchers at the University of Saskatchewan in Saskatoon found that the administration of synthetic cannabinoids in rats stimulated the proliferation of newborn neurons (nerve cells) in the hippocampus region of the brain and significantly reduced measures of anxiety and depression-like behavior. The results shocked researchers -- who noted that almost all other so-called "drugs of abuse," including alcohol and tobacco, decrease neurogenesis in adults -- and left the "pot kills brain cells" crowd with a platter of long-overdue egg on their faces.

While it would be premature to extrapolate the study's findings to humans, at a minimum, the data reinforce the notion that cannabinoids are unusually non-toxic to the brain and that even long-term use of marijuana likely represents little risk to brain function. The findings also offer further evidence that cannabinoids can play a role in the alleviation of depression and anxiety, and that cannabis-based medicines may one day offer a safer alternative to conventional anti-depressant pharmaceuticals such as Paxil and Prozac.

(Reference: Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic and depressant-like effects. The Journal of Clinical Investigation. 2005)

Cannabis & Neuroprotection

Not only has modern science refuted the notion that marijuana is neurotoxic, recent scientific discoveries have indicated that cannabinoids are, in fact, neuroprotective, particularly against alcohol-induced brain damage. In a recent preclinical study -- the irony of which is obvious to anyone who reads it -- researchers at the US National Institutes of Mental Health (NIMH) reported that the administration of the non-psychoactive cannabinoid cannabidiol (CBD) reduced ethanol-induced cell death in the brain by up to 60 percent. "This study provides the first demonstration of CBD as an in vivo neuroprotectant ... in preventing binge ethanol-induced brain injury," the study's authors wrote in the May 2005 issue of the Journal of Pharmacology and Experimental Therapeutics. Alcohol poisoning is linked to hundreds of preventable deaths each year in the United States, according to the Centers for Disease Control, while cannabis cannot cause death by overdose.

Of course, many US neurologists have known about cannabis' neuroprotective prowess for years. NIMH scientists in 1998 first touted the ability of natural cannabinoids to stave off the brain-damaging effects of stroke and acute head trauma. Similar findings were then replicated by investigators in the Netherlands and Italy and, most recently, by a Japanese research in 2005. However, attempts to measure the potential neuroprotective effects of synthetic cannabinoid-derived medications in humans have so far been inconclusive.

(References: Comparison of cannabidiol, antioxidants and diuretics in reversing binge ethanol-induced neurotoxicity. Journal of Pharmacology and Experimental Therapeutics. 2005 | Cannabidiol prevents cerebral infarction. Stroke. 2005 | Post-ischemic treatment with cannabidiol prevents electroencephalographic flattening, hyperlocomotion and neuronal injury in gerbils. Neuroscience Letters. 2003 | Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity. Journal of Neuroscience. 2001 | Cannabidiol and Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proceedings of the National Academy of Sciences. 1998)

Cannabinoids & Glioma

Of all cancers, few are as aggressive and deadly as glioma. Glioma tumors quickly invade healthy brain tissue and are typically unresponsive to surgery and standard medical treatments. One agent they do respond to is cannabis.

Writing in the August 2005 issue of the Journal of Neurooncology, investigators at the California Pacific Medical Center Research Institute reported that the administration of THC on human glioblastoma multiforme cell lines decreased the proliferation of malignant cells and induced apoptosis (programmed cell death) more rapidly than did the administration of the synthetic cannabis receptor agonist, WIN-55,212-2. Researchers also noted that THC selectively targeted malignant cells while ignoring healthy ones in a more profound manner than the synthetic alternative. Patients diagnosed with glioblastoma multiforme typically die within three months without therapy.

Previous research conducted in Italy has also demonstrated the capacity of CBD to inhibit the growth of glioma cells both in vitro (e.g., a petri dish) and in animals in a dose dependent manner. As a result, a Spanish research team is currently investigating whether the intracranial administration of cannabinoids can prolong the lives of patients diagnosed with inoperable brain cancer.

Most recently, a scientific analysis in the October issue of the journal Mini-Reviews in Medicinal Chemistry noted that, in addition to THC and CBD's brain cancer-fighting ability, studies have also shown cannabinoids to halt the progression of lung carcinoma, leukemia, skin carcinoma, colectoral cancer, prostate cancer and breast cancer.

(References: Cannabinoids selectively inhibit proliferation and induce cell death of cultured human glioblastoma multiforme cells. Journal of Neurooncology. 2005 | Cannabinoids and cancer. Mini-Reviews in Medicinal Chemistry. 2005 | Anti-tumor effects of cannabidiol, a non-psychotropic cannabinoid, on human glioma cell lines. Journal of Pharmacology and Experimental Therapeutics. 2003)

Cannabinoids & Neurodegeneration

Emerging evidence also indicates that cannabinoids may play a role in slowing the progression of certain neurodegenerative diseases, such as Multiple Sclerosis, Parkinson's disease, Alzheimer's, and Amyotrophic Lateral Sclerosis (a.k.a. Lou Gehrig's Disease). Recent animal studies have shown cannabinoids to delay disease progression and inhibit neurodegeneration in mouse models of ALS, Parkinson's, and MS. As a result, the Journal of Neurological Sciences recently pronounced, "There is accumulating evidence ... to support the hypothesis that the cannabinoid system can limit the neurodegenerative processes that drive progressive disease," and patient trials investigating whether the use of oral THC and cannabis extracts may slow the progression of MS are now underway in the United Kingdom.

(References: Cannabinoids and neuroprotection in CNS inflammatory disease. Journal of the Neurological Sciences. 2005. Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2004 | Cannabinoids inhibit neurodegeneration in models of multiple sclerosis. Brain. 2003)

Cannabis & Cognition

But what about claims of cannabis' damaging effect of cognition? A review of the scientific literature indicates that rumors regarding the "stoner stupid" stereotype are unfounded. According to clinical trial data published this past spring in the American Journal of Addictions, cannabis use -- including heavy, long-term use of the drug -- has, at most, only a negligible impact on cognition and memory. Researchers at Harvard Medical School performed magnetic resonance imaging on the brains of 22 long-term cannabis users (reporting a mean of 20,100 lifetime episodes of smoking) and 26 controls (subjects with no history of cannabis use). Imaging displayed "no significant differences" between heavy cannabis smokers compared to controls, the study found.

Previous trials tell a similar tale. An October 2004 study published in the journal Psychological Medicine examining the potential long-term residual effects of cannabis on cognition in monozygotic male twins reported "an absence of marked long-term residual effects of marijuana use on cognitive abilities." A 2003 meta-analysis published in the Journal of the International Neuropsychological Society also "failed to reveal a substantial, systematic effect of long-term, regular cannabis consumption on the neurocognitive functioning of users who were not acutely intoxicated," and a 2002 clinical trial published in the Canadian Medical Association Journal determined, "Marijuana does not have a long-term negative impact on global intelligence."

Finally, a 2001 study published in the journal Archives of General Psychiatry found that long-term cannabis smokers who abstained from the drug for one week "showed virtually no significant differences from control subjects (those who had smoked marijuana less than 50 times in their lives) on a battery of 10 neuropsychological tests." Investigators further added, "Former heavy users, who had consumed little or no cannabis in the three months before testing, [also] showed no significant differences from control subjects on any of these tests on any of the testing days."

(References: Lack of hippocampal volume change in long-term heavy cannabis users. American Journal of Addictions. 2005 | Neuropsychological consequences of regular marijuana use: a twin study. Psychological Medicine. 2004 | Non-acute (residual) neurocognitive effects of cannabis use: A meta-analytic study. Journal of the International Neuropsychological Society. 2003 | Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults. Canadian Medical Association Journal. 2002 | Neuropsychological Performance in Long-term Cannabis Users. Archives of General Psychiatry. 2001)

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updated: Feb 14, 2006

[CrackSmokeRepublican]

Looks like they are pushing this evidence to stop further deregulation-decriminalization.  Looks like Cannaboid receptors return after a few weeks.

Chronic Pot Smoking Affects Brain Chemistry, Scans Show

Tue Jun 7, 7:07 pm ET

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TUESDAY, June 7 (HealthDay News) -- Imaging scans show that chronic daily use of marijuana can have a detrimental effect on the brain, according to a new report.

In the study, researchers revealed that chronic use of the drug caused a decrease in the number of receptors involved in a wide array of important mental and bodily functions, including concentration, movement coordination, pleasure, pain tolerance, memory and appetite.

Marijuana, also known as cannabis, is abused more than any other illegal drug in America, according to the U.S. National Institute on Drug Abuse. When smoked or ingested, the drug's psychoactive chemical binds to numerous cannabinoid receptors in the brain and throughout the body, which influence a range of mental states and actions. One of two known types of cannabinoid receptors, called CB1, is involved primarily in the central nervous system.

In conducting the study, researchers compared the brains of 30 chronic daily marijuana smokers to non-smokers over the course of roughly four weeks. Using molecular imaging, researchers were able to visualize changes in the participants' brains and found the cannabinoid CB1 receptors of the smokers had decreased by roughly 20 percent compared to the otherwise healthy people with limited lifetime exposure to marijuana.

"With this study, we were able to show for the first time that people who abuse cannabis have abnormalities of the cannabinoid receptors in the brain," lead author Dr. Jussi Hirvonen said in a Society of Nuclear Medicine news release.

The researchers re-scanned 14 of the smokers after one month of abstinence and found a notable increase in receptor activity in areas that were deficient at the beginning of the study. These findings, the investigators concluded, suggest the adverse effects of chronic marijuana use are reversible.

"This information may prove critical for the development of novel treatments for cannabis abuse. Furthermore, this research shows that the decreased receptors in people who abuse cannabis return to normal when they stop smoking the drug," Hirvonen added.

The study, which was a collaboration between the U.S. National Institute of Mental Health and U.S. National Institute on Drug Abuse, was slated for presentation Monday at the annual meeting of the Society of Nuclear Medicine in San Antonio, Texas. Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Institute on Drug Abuse has more on marijuana and its effects on the brain.

http://news.yahoo.com/s/hsn/20110607/hl ... show/print

[CrackSmokeRepublican]

Marijuana Saved My Sons Life - Marijuana and Autism ABC Worldwide News Diane Sawyer


 :think:

[youtube:17djv2rt]http://www.youtube.com/watch?v=vjlBXtd8PRQ[/youtube]17djv2rt]

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Prostate Cancer Cured with Cannabis Oil

Spiral Up With Ava Marie  - Dennis Hill, Biochemist cures his cancer with cannabinoid oil


[youtube:gbh9vk3z]http://www.youtube.com/watch?v=ym0BSdEIjJA[/youtube]gbh9vk3z]


[youtube:gbh9vk3z]http://www.youtube.com/watch?v=G_7gy7Dyta0[/youtube]gbh9vk3z]


Spiral Up With Ava Marie  - Dennis Hill, Biochemist cures his cancer with cannabinoid oil.

Rick Simpson and Christian Laurette have "given" you the recipe to cure yourself.... free of charge. Hemp oil (cannabinoid oil) is not sold in stores, that is "Hemp seed oil" and it is good for you but it won't cure diseases or help with pain. Hemp oil IS cannabinoids extracted from the buds of the female marijuana/hemp plant. You have to get buds or this will not be potent enough to cure serious disease; this has been proven... take my word on it or take your chances with your doctor.


RUN FROM THE CURE: The Rick Simpson Story, a film by Christian Laurette
Available for free at http://www.youtube.com/chrychek

RUN FROM THE CURE: The Rick Simpson Story...
"IF YOU SEE ONLY ONE DOCUMENTARY THIS YEAR... MAKE IT THIS ONE!"
"THIS MOVIE SAVED MY LIFE!"
"I CURED MY CANCER WITH CANNABIS OIL!"


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Rick Simpson Croatia Seminar 2011 FORBIDDEN CURE


[youtube:gbh9vk3z]http://www.youtube.com/watch?v=nJi-_eqqubk[/youtube]gbh9vk3z]



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[ahaze]

Thanks for those latest finds /tab.  Its all stranger than fiction to me now, but this thread got me pulling on other threads and I'm watching all kinds of real life dramas unfold amidst this dawning reality.  Below is the latest piece on newly discovered benefits of cannabinoid therapy I've come across, not in the least ironically revealed by the unfortunate situation of Marc Emery (B.C. cannabis activist).  Many are aware Marc was extradited from Canada to be imprisoned by the U.S. for his bombastic ways with hemp, but even more unfortunately Marc contracted MRSA while in Federal prison and the following article-reference-link describing Marc's situation revealed the subsequent repro'd article on MRSA cannabinoid therapy I suspect a few out here will appreciate.

Prince of Pot Marc Emery Catches "Superbug" in US Prison
_http://stopthedrugwar.org/chronicle/2011/jul/11/prince_pot_marc_emery_catches_su

_http://www.technologyreview.com/biomedicine/21366/
A New MRSA Defense

Marijuana extracts kill antibiotic-resistant MRSA without a high.
Friday, September 12, 2008
By Nora Schultz

Substances harvested from cannabis plants could soon outshine conventional antibiotics in the escalating battle against drug-resistant bacteria. The compounds, called cannabinoids, appear to be unaffected by the mechanism that superbugs like MRSA use to evade existing antibiotics. Scientists from Italy and the United Kingdom, who published their research in the Journal of Natural Products last month, say that cannabis-based creams could also be developed to treat persistent skin infections.

Cannabis has long been known to have antibacterial properties and was studied in the 1950s as a treatment for tuberculosis and other diseases. But research into using cannabis as an antibiotic has been limited by poor knowledge of the plant's active ingredients and by the controversy surrounding its use as a recreational drug.

Now Giovanni Appendino of the Piemonte Orientale University, in Italy, and Simon Gibbons of the School of Pharmacy at the University of London, U.K., have revisited the antibiotic power of marijuana by systematically testing different cannabinoids' ability to kill MRSA.

MRSA, short for methicillin-resistant Staphylococcus aureus, is a bacterium that can cause difficult-to-treat infections since it does not respond to many antibiotics. Many healthy people carry S. aureus on their skin, but problems arise when multi-drug-resistant strains infect people with weak immune systems through an open wound. In the worst cases, the bug spreads throughout the body, causing a life-threatening infection.

To make matters worse, resistance to antibiotics is rapidly increasing, and some strains are now even immune to vancomycin, a powerful antibiotic that is normally used only as a last resort when other drugs fail.

But when Appendino, Gibbons, and their colleagues applied extracts from five major cannabinoids to bacterial cultures of six strains of MRSA, they discovered that the cannabinoids were as effective at killing the bugs as vancomycin and other antibiotics.

"The cannabinoids even showed exceptional activity against the MRSA strain that makes extra amounts of the proteins that give the bugs resistance against many antibiotics," says Gibbons. These proteins, he explains, allow the bacteria to "hoover up unwanted things from inside the cell and spit them out again."

Conveniently, of the five cannabinoids tested by the researchers, the two most effective ones also happen to be nonpsychoactive, meaning that they cannot cause a high. "What this means is, we could use fiber hemp plants that have no use as recreational drugs to cheaply and easily produce potent antibiotics," says Appendino.

In an attempt to discover how the cannabinoids kill MRSA, the team manipulated several chemical groups within the compounds. Most of the changes did not affect the antibiotic activity at all, and those that did seemed to influence only how well the cannabinoid is taken up by the bacterial cells.

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History of Cannabis and Its Preparations in Saga, Science, and Sobriquet
by Ethan B. Russo

In 1976, an important translation of the Fayyum Medical Book was published [101],
a document written in Egyptian Demotic script dating to the second half of the 2nd
century c.e. This seemed to represent a compilation of knowledge back to the 6th
century b.c., and, while the format is reminiscent of the Ebers Papyrus, there is very
little overlap in content. Strong parallels can be noted to the materia medica of Pliny,
Galen, and Dioscorides with support for the concept that the flow of medical
knowledge of the time was from Alexandria to Greece and Rome rather than vice
versa. The treatises of greatest interest here concerns curing of 'ryty-tumors' consisting
of sores, swellings, abscesses, and tumors, as well as those pertaining to fevers and
diseases of the ear. The Demotic term for cannabis was m^vy.

Under ryty-tumors, we see the following [101] (p. 101):

Method 3

Another (prescription) for curing the tumour [. . .] [to be tritu]rated finely; fine
powder to be made [. . .]. Another (prescription): mecon [. . .] cannabis according to
CHEMISTRY & BIODIVERSITY – Vol. 4 (2007) 1625
that which is above; another: resin of pine, chalcedony, according [. . .] ash of
[cadmia] kite [?], cannabis kite; to be bandaged over it.

Subsequently, we see [101] (p. 103):

Method 4

[. . .] to paralyse [the tu]mours: extract of herbs, papyrus, sap of the hur-tree, lotus
leaf, cannabis, [. . .], heated [. . .], sweet clover [. . .].
[. . .]

Another (prescription): heated cannabis, sulphate of copper, ammoniac salt, to be
triturated finely with (extract of) waterparsnip; to cause them to appear [. . .].
The latter passage is particularly interesting in its specification for heated cannabis,
suggesting that decarboxylation of phytocannabinoid precursors might have been
operative. Interestingly, centuries later, Marcandier published his Traite´ du chanvre
[102], claiming benefit of cannabis on tumors (p. 38): 'The seed and the green leaves,
crushed and applied in the form of cataplasm, to painful tumors, appear to be strongly
resolutive and intoxicating' [translation E. B. R.]. It has been well-established that all
the phytocannabinoids are active cytotoxics in a variety of cancer cell lines [103] [104].
Marcandier echoed earlier claims of the herbalist Parkinson that cannabis roots were
effective for tumors and other inflammation in 1640 in the Theatrum Botanicum, The
Theater of Plants [105] (p. 598):
[. . .] 'the same decoction of the rootes, easeth the paines of the goute, the hard
tumours, or knots of the joynts, the paines and shrinking of the sinewes, and other the
like paines of the hippes: it is good to be used, for any place that hath beene burnt by
fire, if the fresh juyce be mixed with a little oyle or butter'.

Cannabis roots have proven to harbor terpenoids, sterols [106], and alkaloids [107], but
no cannabinoids. Cannabis roots have received little research attention in recent decades.

The book as PDF
http://dcsafeaccess.org/wp-content/uplo ... y-2007.pdf

[youtube:1q69z24w]http://www.youtube.com/watch?v=XzRIZbzRyzE[/youtube]1q69z24w]

http://www.google.com/search?hl=sv&q=cy ... 80&bih=886

http://current.com/news-and-politics/89 ... t-tomb.htm

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[Blealge]

Hello

Here was a debate in relation to how many states are legal for CBD.
I found something about it on this blog:
While 33 stated have legalized medical marijuana, the remaining 17 states have all passed laws allowing the use of cannabidiol (CBD) extract, usually in oil form, with minimal tetrahydrocannabinol (THC), and often for the treatment of epilepsy or seizures in seriously ill children.